Biopharmaca BiofarmakaPotency of Indonesian Medicinal Plants as Tyrosinase Inhibitor and Antioxidant Agent
Vinaora Nivo SliderVinaora Nivo SliderVinaora Nivo SliderVinaora Nivo Slider

BRC SosMed

 facebook   google plus    twitter    linkedin    youtube  
 
           youtube

Home

JOURNAL 2010
Potency of Indonesian Medicinal Plants as Tyrosinase Inhibitor and Antioxidant Agent

Please use this identifier to cite or link to this item
http://biofarmaka.ipb.ac.id/publication/journal/146-potency-of-indonesian-medicinal-plants-as-tyrosinase-inhibitor-and-antioxidant-agent
Title 

Potency of Indonesian Medicinal Plants as Tyrosinase Inhibitor and Antioxidant Agent

Authors
 
:
 
Irmanida Batubara1,5, Latifah K. Darusman1,5, Tohru Mitsunaga2, Min Rahminiwati3,5 and Edy Djauhari4,5
Corporates







 
:






 
 

1Departement of Chemistry, Faculty of Mathematics & Natural Sciences, Bogor Agricultural University, Indonesia.
2Department of Applied Science, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
3Department of Department Anatomy, Physiology, Pharmacology, Faculty of Veterinary Medicine, Bogor Agricultural University, Indonesia.
4Department of Biochemistry, Faculty of Mathematics & Natural Sciences, Bogor Agricultural University, Indonesia.
5Biopharmaca Research Center, Institute of Research & Community Services, Bogor Agricultural University, Indonesia.

Issue Date : March 2010
Publisher : Journal of Biological Sciences
Series / Report No :
 
eISSN: 1812-5719 pISSN: 1727-3048
DOI: 10.3923/jbs.2010.138.144
Physical Description :
 
2010 Vol. 10 No. 2, p 138-144
 
Language : en
Abstract











 
:











 

The aim of this study is to screen whitening agent potency of 45 Indonesian plant materials from 35 species. All plant materials were extracted with methanol and 50% ethanol which resulted to 90 extracts. The methods for screening is based on tyrosinase inhibitor potency using mushroom tyrosinase and antioxidant activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH). Scoring method was used to identify the best extract as whitening agent. Out of 90 extracts, merbau (Intsia palembanica) methanol and 50% ethanol extracts are the most potent extracts as tyrosinase inhibitor (for monophenolase and diphenolase). Their IC50 values are not significantly different with kojic acid as positive control. Based on antioxidant activity, merbau methanol extract (IC50: 3.87 μg mL-1) is the best antioxidant together with kayu putih (Melaleuca cajuputi) ethanol 50% extract (IC50: 5.76 μg mL-1) and Rhizopora sp. methanol extract (IC50: 5.90 μg mL-1). Their IC50 values are not significantly different with (+)-catechin (IC50: 2.94 μg mL-1) as positive control. In conclusion, merbau methanol extract is the most potent extract as whitening agent based on scoring data from its tyrosinase inhibitory and antioxidant activities.

Source url
 
:
 

http://biofarmaka.ipb.ac.id/publication/journal/146-potency-of-indonesian-medicinal-plants-as-tyrosinase-inhibitor-and-antioxidant-agent

Mesh :

 

Keywords : Indonesian plants, tyrosinase inhibitor, antioxidant
How to cite this article
 
:


 

Batubara, I., L.K. Darusman, T. Mitsunaga, M. Rahminiwati and E. Djauhari. 2010. Potency of Indonesian Medicinal Plants as Tyrosinase Inhibitor and Antioxidant Agent. Journal of Biological Sciences, 10(2): 138-144.
url: http://biofarmaka.ipb.ac.id/publication/journal/146-potency-of-indonesian-medicinal-plants-as-tyrosinase-inhibitor-and-antioxidant-agent

   

 

Download Fulltext.


<ta>

Back to BRC Journal.....

BRC Site Statistics

  • Unique Visits Today313
  • Unique Visits Yesterday24
  • Visits This Week1406
  • Visits Previous Week1300