Biopharmaca BiofarmakaIndonesian Kepel Fruit as Oral Deodorant


Indonesian Kepel Fruit as Oral Deodorant

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Indonesian Kepel Fruit (Stelechocarpus burahol) as Oral Deodorant


H.S. Darusman1,2, M. Rahminiwati1,2, S. Sadiah1,2, I. Batubara2,3, L.K. Darusman2,3,* and T. Mitsunaga4



1Departement of Anatomy, Physiology and Pharmacology, Faculty of Veterinary Medicine, Bogor Agricultural University, Indonesia
2Biopharmaca Research Center, Bogor Agricultural University, Jl Taman Kencana No. 3 Bogor 16128, Indonesia
3Departement of Chemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University, IPB Darmaga Campus, Bogor, Indonesia
4Faculty of Applied Biological Science, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan
*Corresponding Author: L.K. Darusman, Biopharmaca Research Center, Bogor Agricultural University, Jl. Taman Kencana No. 3, Bogor 16128. Telp +62-251-8373561 Fax +62+251+8347525 Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Issue Date : November 02, 2011
Publisher : Research Journal of Medicinal Plant
Series / Report No :
ISSN 1819-3455 / DOI: 10.3923/rjmp.2012.180.188
Physical Description :
2012, Volume: 6, Issue: 2, Page No.: 180-188
Language : en


Kepel (Stelechocarpus burahol) fruit has been known to have efficacy as an oral deodorant in Java Island, Indonesia for a long time. The research aimed on Indonesian Herbal Kepel as deodorant agent for reducing fecal odorants which are ammonia, trimethyl-amine and phenol. Pharmacological screening test was conducted by measuring the adsorbent activities of Kepel’s fruit (pulp, seed and peel) to odorants which can be emitted from feces, such as ammonia (NH3) and methyl-mercaptan (CH3SH). To confirm it ability as an oral deodorant, in vivo test was performed by applying it orally on rats. Kepel’s fruits pulp powder was regarded as the best absorbent agent (adsorbed 62.96 and 77.78% for NH3 and CH3SH, respectively). All fecal odorant on the 3rd and 7th day oral application result showed a significant decrease (p<0.05). Beside the odorant adsorption, it also activates the probiotic Bifidobacter sp. by increasing its population. In conclusion, kepel had a potential pharmacological activity as an oral deodorant through its adsorbent function and probiotic activation.
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Mesh :


Keywords Kepel (Stelechocarpus burahol), Oral Deodorants, prebiotics, adsorbent, fecal odorants
How to cite this article


H.S. Darusman, M. Rahminiwati, S. Sadiah, I. Batubara, L.K. Darusman and T. Mitsunaga, 2012. Indonesian Kepel Fruit (Stelechocarpus burahol) as Oral Deodorant. Research Journal of Medicinal Plant, 6(2): 180-18 
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